Essay of malignant tumours and environment problems

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Klin Onkol 1992; 5(2): 35-38.

The causative relations between environment and cancer are generally accepted but they are far from being simple. The epidemiologists demonstrated that the environmental complex is responsible for 70 to 90 percent of all new cancer cases. However, one should be fully aware of the precise meaning of the term "environment". The meaning may not be narrowed to the sole problem of environmental pollution. Similarly the cancer of various topographic location beeing also of heterogenous histogenesis are probable associated with various causative factors. On the other hand there are the specific problems of using of statistical operations based on small series of cases. For example a high age standardized cancer incidence in some of waste regions of Czech republic is analyzed in the article and the author points out in this regard that the statistical tools and interpretation of results should be in the hand of expert epidemiologists.