Klin Onkol 2026; 39(4): 238-254.
DOI: 10.48095/ccko2026238.
Keywords: IgG4-related disease – rituximab – inebilizumab – obinutuzumab – obexelimab – aortitis – retroperitoneal fibrosis – sialadenitis – Mikulicz syndrome
Authors: Adam Zdeněk, Doubek Michael, Řehák Zdeněk, Zbořil Vladimír, Kubeš Václav , Borský Marek, Adamová Zuzana, Čermák Aleš, König Jiří, Boichuk Ivanna, Štork Martin, Pour Luděk2026-08-15:IgG4-related disease – treatment with anti-CD20, anti-CD19 antibodies, and other new drugs
Keywords: IgG4-related disease – rituximab – inebilizumab – obinutuzumab – obexelimab – aortitis – retroperitoneal fibrosis – sialadenitis – Mikulicz syndrome
Authors: Adam Zdeněk, Doubek Michael, Řehák Zdeněk, Zbořil Vladimír, Kubeš Václav , Borský Marek, Adamová Zuzana, Čermák Aleš, König Jiří, Boichuk Ivanna, Štork Martin, Pour Luděk2026-08-15:IgG4-related disease – treatment with anti-CD20, anti-CD19 antibodies, and other new drugs
Klin Onkol 2026; 39(4): 255-261.
DOI: 10.48095/ccko2026255.
Keywords: Erdheim-Chester disease – anakinra – cladribine – interferon alfa – vemurafenib – dabrafenib – trametinib – cobimetinib
Authors: Adam Zdeněk, Štork Martin, Řehák Zdeněk, Boichuk Ivanna, Krejčí Marta, Pour Luděk2026-08-15:Treatment of Erdheim-Chester disease from the perspective in 2026
Keywords: Erdheim-Chester disease – anakinra – cladribine – interferon alfa – vemurafenib – dabrafenib – trametinib – cobimetinib
Authors: Adam Zdeněk, Štork Martin, Řehák Zdeněk, Boichuk Ivanna, Krejčí Marta, Pour Luděk2026-08-15:Treatment of Erdheim-Chester disease from the perspective in 2026
Klin Onkol 2026; 39(4): 262-265.
DOI: 10.48095/ccko2026262.
Keywords: human papillomavirus – cervical cancer – cervical intraepithelial neoplasia – screening – prophylactic vaccination – HPV diagnosis
Authors: Mihal Juríková Zuzana, Hernychová Lenka2026-08-15:HPV infection and its significance in the development and prevention of cervical cancer
Keywords: human papillomavirus – cervical cancer – cervical intraepithelial neoplasia – screening – prophylactic vaccination – HPV diagnosis
Authors: Mihal Juríková Zuzana, Hernychová Lenka2026-08-15:HPV infection and its significance in the development and prevention of cervical cancer
Klin Onkol 2026; 39(4): 266-275.
DOI: 10.48095/ccko2026266.
Keywords: early luminal breast cancer – Window of Opportunity – Ki-67 – multigene assays – adjuvant therapy, prognosis
Authors: Bielčiková Zuzana, Zimovjanová Martina, Kindl Jan2026-08-15:Strategies for utilizing Ki67 and multigene assays as a window of opportunity in the treatment of HR+/HER2– early breast cancer in clinical practice
Keywords: early luminal breast cancer – Window of Opportunity – Ki-67 – multigene assays – adjuvant therapy, prognosis
Authors: Bielčiková Zuzana, Zimovjanová Martina, Kindl Jan2026-08-15:Strategies for utilizing Ki67 and multigene assays as a window of opportunity in the treatment of HR+/HER2– early breast cancer in clinical practice
Klin Onkol 2026; 39(4): 276-286.
DOI: 10.48095/ccko2026276.
Keywords: cryotherapy – freezing – imaging, three-dimensional – ice ball –size
Authors: de Palma Angelica, Cortese Francesco, Di Giovanni Giuseppe, Acquafredda Fabrizio, Pisani Antonio Rosario, Inchingolo Riccardo2026-08-15:Evaluation of ice ball size as a function of freezing intensity through computed tomography scans during cryoablation procedures
Keywords: cryotherapy – freezing – imaging, three-dimensional – ice ball –size
Authors: de Palma Angelica, Cortese Francesco, Di Giovanni Giuseppe, Acquafredda Fabrizio, Pisani Antonio Rosario, Inchingolo Riccardo2026-08-15:Evaluation of ice ball size as a function of freezing intensity through computed tomography scans during cryoablation procedures
Klin Onkol 2026; 39(4): 287-293.
DOI: 10.48095/ccko2026287.
Keywords: non-small-cell lung carcinoma – next-generation sequencing – FGFR2 fusion – pemigatinib – pancreatobiliary adenocarcinoma
Authors: Pešek Miloš, Drösslerová Marie, Vaněček Tomáš, Bocko Jozef 2026-08-15:FGFR2 fusion as the key to targeted therapy – a case report with a diagnostic turning point
Keywords: non-small-cell lung carcinoma – next-generation sequencing – FGFR2 fusion – pemigatinib – pancreatobiliary adenocarcinoma
Authors: Pešek Miloš, Drösslerová Marie, Vaněček Tomáš, Bocko Jozef 2026-08-15:FGFR2 fusion as the key to targeted therapy – a case report with a diagnostic turning point
Klin Onkol 2026; 39(4): 294-301.
DOI: 10.48095/ccko2026294.
Keywords: fibrous dysplasia – monoclonal gammopathy of undetermined significance – MGUS – PET/CT imaging – denosumab – bisphosphonates
Authors: Řehák Zdeněk, Ptáčník Václav, Adam Zdeněk, Koukalová Renata, Straub Jan, Křiva Tomáš, Adamová Zuzana, Křivanová Andrea, Boichuk Ivanna, Pour Luděk2026-08-15:Contribution of bone scintigraphy and PET/CT in the differential diagnosis of bone involvement in a patient with fibrous dysplasia and monoclonal gammopathy of undetermined significance and fibrous dysplasia treatment with denosumab
Keywords: fibrous dysplasia – monoclonal gammopathy of undetermined significance – MGUS – PET/CT imaging – denosumab – bisphosphonates
Authors: Řehák Zdeněk, Ptáčník Václav, Adam Zdeněk, Koukalová Renata, Straub Jan, Křiva Tomáš, Adamová Zuzana, Křivanová Andrea, Boichuk Ivanna, Pour Luděk2026-08-15:Contribution of bone scintigraphy and PET/CT in the differential diagnosis of bone involvement in a patient with fibrous dysplasia and monoclonal gammopathy of undetermined significance and fibrous dysplasia treatment with denosumab
Klin Onkol 2026; 39(4): 302-304.
DOI: 10.48095/ccko2026302.
Keywords: 18F-FDG-PET/CT
Authors: Řehák Zdeněk, Adam Zdeněk, Horváth Teodor, Vašina Jiří, Koukalová Renata, Fabián Pavel, Adam Jan2026-08-15:18F-FDG-PET/CT in the diagnosis of lymphadenopathy
Keywords: 18F-FDG-PET/CT
Authors: Řehák Zdeněk, Adam Zdeněk, Horváth Teodor, Vašina Jiří, Koukalová Renata, Fabián Pavel, Adam Jan2026-08-15:18F-FDG-PET/CT in the diagnosis of lymphadenopathy
Klin Onkol 2026; 39(3): 150-168.
DOI: 10.48095/ccko2026150.
Keywords: histiocytosis
Authors: Adam Zdeněk, Eid Michal, Řehák Zdeněk, Kubeš Václav , Horváth Teodor, Doubková Martina, Starý Karel, Šlampa Pavel, Čermák Aleš, Fadrus Pavel, Adamová Zuzana, Vaníček Jiří, Nebeský Tomáš, Kamarádová Kateřina, Boichuk Ivanna, Pour Luděk2026-06-15:Clinical presentations of the most common histiocytic disorders
Keywords: histiocytosis
Authors: Adam Zdeněk, Eid Michal, Řehák Zdeněk, Kubeš Václav , Horváth Teodor, Doubková Martina, Starý Karel, Šlampa Pavel, Čermák Aleš, Fadrus Pavel, Adamová Zuzana, Vaníček Jiří, Nebeský Tomáš, Kamarádová Kateřina, Boichuk Ivanna, Pour Luděk2026-06-15:Clinical presentations of the most common histiocytic disorders
Klin Onkol 2026; 39(3): 169-183.
DOI: 10.48095/ccko2026169.
Keywords: Castleman disease
Authors: Adam Zdeněk, Kamarádová Kateřina, Doubková Martina, Řehák Zdeněk, Koukalová Renata, Křivanová Andrea, Horváth Teodor, Čermák Aleš, Boichuk Ivanna, Štork Martin, Sandecká Viera, Adamová Zuzana, Pour Luděk2026-06-15:Chronic low-grade fever or fever with mild lymphadenopathy may indicate Castleman disease if no malignant, autoimmune, or infectious cause of the lymphadenopathy is identified
Keywords: Castleman disease
Authors: Adam Zdeněk, Kamarádová Kateřina, Doubková Martina, Řehák Zdeněk, Koukalová Renata, Křivanová Andrea, Horváth Teodor, Čermák Aleš, Boichuk Ivanna, Štork Martin, Sandecká Viera, Adamová Zuzana, Pour Luděk2026-06-15:Chronic low-grade fever or fever with mild lymphadenopathy may indicate Castleman disease if no malignant, autoimmune, or infectious cause of the lymphadenopathy is identified
Klin Onkol 2026; 39(3): 184-194.
DOI: 10.48095/ccko2026184.
Keywords: endometrial cancer – systemic treatment – chemotherapy – immunotherapy – second and subsequent lines of therapy – pembrolizumab – lenvatinib
Authors: Bednaříková Markéta, Koblížková Michaela, Ovesná Petra, Hausnerová Jitka, Ehrlichová Lucie, Felsinger Michal , Tomková Martina, Minář Luboš, Weinberger Vít2026-06-15:Second and subsequent lines of systemic therapy in endometrial cancer – a real-life clinical experience
Keywords: endometrial cancer – systemic treatment – chemotherapy – immunotherapy – second and subsequent lines of therapy – pembrolizumab – lenvatinib
Authors: Bednaříková Markéta, Koblížková Michaela, Ovesná Petra, Hausnerová Jitka, Ehrlichová Lucie, Felsinger Michal , Tomková Martina, Minář Luboš, Weinberger Vít2026-06-15:Second and subsequent lines of systemic therapy in endometrial cancer – a real-life clinical experience
Klin Onkol 2026; 39(3): 195-198.
DOI: 10.48095/ccko2026195.
Keywords: cholangiocarcinoma – targeted therapy – pemigatinib – FGFR tyrosine kinase inhibitor
Authors: Bohuňovská Kateřina2026-06-15:From progression to complete remission – a case study of successful pemigatinib treatment in a patient with metastatic FGFR2+ cholangiocarcinoma
Keywords: cholangiocarcinoma – targeted therapy – pemigatinib – FGFR tyrosine kinase inhibitor
Authors: Bohuňovská Kateřina2026-06-15:From progression to complete remission – a case study of successful pemigatinib treatment in a patient with metastatic FGFR2+ cholangiocarcinoma
Klin Onkol 2026; 39(3): 199-211.
DOI: 10.48095/ccko2026199.
Keywords: Erdheim-Chester disease – FDG-PET/CT – NaF-PET/CT – skeletal scintigraphy – anakinra – cladribine
Authors: Řehák Zdeněk, Stejskal Václav, Adam Zdeněk, Kamarádová Kateřina, Štěpánková Pavla, Soboličová Sandra, Ošmera Pavel, Starý Karel, Nehyba Svatopluk, Čermák Aleš, Standara Michal, Pour Luděk2026-06-15:Differences in the imaging of Erdheim-Chester disease using FDG-PET/CT, NaF-PET/CT examinations, and skeletal scintigraphy. Regression of the disease after treatment with cladribine combined with cyclophosphamide and anakinra
Keywords: Erdheim-Chester disease – FDG-PET/CT – NaF-PET/CT – skeletal scintigraphy – anakinra – cladribine
Authors: Řehák Zdeněk, Stejskal Václav, Adam Zdeněk, Kamarádová Kateřina, Štěpánková Pavla, Soboličová Sandra, Ošmera Pavel, Starý Karel, Nehyba Svatopluk, Čermák Aleš, Standara Michal, Pour Luděk2026-06-15:Differences in the imaging of Erdheim-Chester disease using FDG-PET/CT, NaF-PET/CT examinations, and skeletal scintigraphy. Regression of the disease after treatment with cladribine combined with cyclophosphamide and anakinra
Klin Onkol 2026; 39(3): 212-214.
DOI: 10.48095/ccko2026212.
Authors: Řehák Zdeněk, Brychta Jindřich, Bencsiková Beatrix, Hendrych Michal, Balážová Zuzana, Jančálek Radim2026-06-15:68Ga-DOTATOC PET/CT – a case report of synchronous oncological duplicity with high expression of somatostatin receptors
Authors: Řehák Zdeněk, Brychta Jindřich, Bencsiková Beatrix, Hendrych Michal, Balážová Zuzana, Jančálek Radim2026-06-15:68Ga-DOTATOC PET/CT – a case report of synchronous oncological duplicity with high expression of somatostatin receptors
Klin Onkol 2026; 39(2): 86-98.
DOI: 10.48095/ccko202686.
Keywords: Castleman disease – siltuximab – rituximab – anakinra – ruxolitinib – sirolimus – rapamycin – daratumab – bortezomib
Authors: Adam Zdeněk, Řehák Zdeněk, Boichuk Ivanna, Horváth Teodor, Adamová Zuzana, Štork Martin, Pour Luděk2026-04-15:Treatment of Castleman disease from the perspective of the year 2026
Keywords: Castleman disease – siltuximab – rituximab – anakinra – ruxolitinib – sirolimus – rapamycin – daratumab – bortezomib
Authors: Adam Zdeněk, Řehák Zdeněk, Boichuk Ivanna, Horváth Teodor, Adamová Zuzana, Štork Martin, Pour Luděk2026-04-15:Treatment of Castleman disease from the perspective of the year 2026