The significance of minimal residual disease and methods of its detection in patients with hematological malignancies

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Klin Onkol 2003; 16(2): 41-48.

Summary: The rapid development of cytogenetics, flow cytometry and molecular biology broadens the spectrum of options for minimal residual disease detection. A brief overview of the most frequently used laboratory techniques is given in the general part. The specialized part summarizes the data from literature concerning the clinical significance of the minimal residual disease detection in certain hematological malignancies.

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