Extravasation of Cytostatic Drugs – Prevention and Best Practices

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Klin Onkol 2016; 29(2): 93-99. DOI: 10.14735/amko201693.

Extravasation is the leakage of a drug (intended primarily for intravenous administration) into
tissues surrounding the vascular system. The damage to surrounding varies depending on the
nature and volume of extravasation. Cytostatic extravasation is associated with poor outcomes
for patients. This paper summarizes the types of risk associated with cytostatic extravasation,
and the preventative measures that can be used when such an event occurs. We also provide
information on potential treatments. However, justifi cation for their use has only been substantiated in papers with diff erent levels of signifi cance and these papers are not available in all countries. We summarize current international recommendations for actions to be taken in
the event of extravasation.

http://dx.doi.org/10.14735/amko201693

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