Klin Onkol 2025; 38(6): 427-435. DOI: 10.48095/ccko2025427.
Background: Childhood cancer is a serious health issue that still does not receive sufficient attention on a global scale compared to cancer in adults. Specialized pediatric cancer registries play a crucial role in collecting detailed data on tumor types, treatment outcomes, genetic determinants, predisposition syndromes, and long-term treatment toxicity. Aim: The aim of this review is to emphasize the importance of collaboration between general and specialized pediatric cancer registries in epidemiological research of childhood malignancies and its impact on improving completeness of ascertainment, diagnosis, treatment, and follow-up care. Conclusion: The effective integration of data collected in general and pediatric cancer registries improves data quality and enables analysis of all relevant data, leading to advances in research, optimization of treatment, and improvement in the quality of care for pediatric cancer patients.