In the current issue:
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IgG4-related disease – treatment with anti-CD20, anti-CD19 antibodies, and other new drugs
Adam Zdeněk et al. -
Strategies for utilizing Ki67 and multigene assays as a window of opportunity in the treatment of HR+/HER2– early breast cancer in clinical practice
Bielčiková Zuzana et al. -
FGFR2 fusion as the key to targeted therapy – a case report with a diagnostic turning point
Pešek Miloš et al.
Reviews
Klin Onkol 2026; 39(4): 238-254.
DOI: 10.48095/ccko2026238.
Keywords: IgG4-related disease – rituximab – inebilizumab – obinutuzumab – obexelimab – aortitis – retroperitoneal fibrosis – sialadenitis – Mikulicz syndrome
Authors: Adam Zdeněk, Doubek Michael, Řehák Zdeněk, Zbořil Vladimír, Kubeš Václav , Borský Marek, Adamová Zuzana, Čermák Aleš, König Jiří, Boichuk Ivanna, Štork Martin, Pour Luděk2026-08-15:IgG4-related disease – treatment with anti-CD20, anti-CD19 antibodies, and other new drugs
Keywords: IgG4-related disease – rituximab – inebilizumab – obinutuzumab – obexelimab – aortitis – retroperitoneal fibrosis – sialadenitis – Mikulicz syndrome
Authors: Adam Zdeněk, Doubek Michael, Řehák Zdeněk, Zbořil Vladimír, Kubeš Václav , Borský Marek, Adamová Zuzana, Čermák Aleš, König Jiří, Boichuk Ivanna, Štork Martin, Pour Luděk2026-08-15:IgG4-related disease – treatment with anti-CD20, anti-CD19 antibodies, and other new drugs
Klin Onkol 2026; 39(4): 255-261.
DOI: 10.48095/ccko2026255.
Keywords: Erdheim-Chester disease – anakinra – cladribine – interferon alfa – vemurafenib – dabrafenib – trametinib – cobimetinib
Authors: Adam Zdeněk, Štork Martin, Řehák Zdeněk, Boichuk Ivanna, Krejčí Marta, Pour Luděk2026-08-15:Treatment of Erdheim-Chester disease from the perspective in 2026
Keywords: Erdheim-Chester disease – anakinra – cladribine – interferon alfa – vemurafenib – dabrafenib – trametinib – cobimetinib
Authors: Adam Zdeněk, Štork Martin, Řehák Zdeněk, Boichuk Ivanna, Krejčí Marta, Pour Luděk2026-08-15:Treatment of Erdheim-Chester disease from the perspective in 2026
Klin Onkol 2026; 39(4): 262-265.
DOI: 10.48095/ccko2026262.
Keywords: human papillomavirus – cervical cancer – cervical intraepithelial neoplasia – screening – prophylactic vaccination – HPV diagnosis
Authors: Mihal Juríková Zuzana, Hernychová Lenka2026-08-15:HPV infection and its significance in the development and prevention of cervical cancer
Keywords: human papillomavirus – cervical cancer – cervical intraepithelial neoplasia – screening – prophylactic vaccination – HPV diagnosis
Authors: Mihal Juríková Zuzana, Hernychová Lenka2026-08-15:HPV infection and its significance in the development and prevention of cervical cancer
Original articles
Klin Onkol 2026; 39(4): 266-275.
DOI: 10.48095/ccko2026266.
Keywords: early luminal breast cancer – Window of Opportunity – Ki-67 – multigene assays – adjuvant therapy, prognosis
Authors: Bielčiková Zuzana, Zimovjanová Martina, Kindl Jan2026-08-15:Strategies for utilizing Ki67 and multigene assays as a window of opportunity in the treatment of HR+/HER2– early breast cancer in clinical practice
Keywords: early luminal breast cancer – Window of Opportunity – Ki-67 – multigene assays – adjuvant therapy, prognosis
Authors: Bielčiková Zuzana, Zimovjanová Martina, Kindl Jan2026-08-15:Strategies for utilizing Ki67 and multigene assays as a window of opportunity in the treatment of HR+/HER2– early breast cancer in clinical practice
Klin Onkol 2026; 39(4): 276-286.
DOI: 10.48095/ccko2026276.
Keywords: cryotherapy – freezing – imaging, three-dimensional – ice ball –size
Authors: de Palma Angelica, Cortese Francesco, Di Giovanni Giuseppe, Acquafredda Fabrizio, Pisani Antonio Rosario, Inchingolo Riccardo2026-08-15:Evaluation of ice ball size as a function of freezing intensity through computed tomography scans during cryoablation procedures
Keywords: cryotherapy – freezing – imaging, three-dimensional – ice ball –size
Authors: de Palma Angelica, Cortese Francesco, Di Giovanni Giuseppe, Acquafredda Fabrizio, Pisani Antonio Rosario, Inchingolo Riccardo2026-08-15:Evaluation of ice ball size as a function of freezing intensity through computed tomography scans during cryoablation procedures
Case report
Klin Onkol 2026; 39(4): 287-293.
DOI: 10.48095/ccko2026287.
Keywords: non-small-cell lung carcinoma – next-generation sequencing – FGFR2 fusion – pemigatinib – pancreatobiliary adenocarcinoma
Authors: Pešek Miloš, Drösslerová Marie, Vaněček Tomáš, Bocko Jozef 2026-08-15:FGFR2 fusion as the key to targeted therapy – a case report with a diagnostic turning point
Keywords: non-small-cell lung carcinoma – next-generation sequencing – FGFR2 fusion – pemigatinib – pancreatobiliary adenocarcinoma
Authors: Pešek Miloš, Drösslerová Marie, Vaněček Tomáš, Bocko Jozef 2026-08-15:FGFR2 fusion as the key to targeted therapy – a case report with a diagnostic turning point
Klin Onkol 2026; 39(4): 294-301.
DOI: 10.48095/ccko2026294.
Keywords: fibrous dysplasia – monoclonal gammopathy of undetermined significance – MGUS – PET/CT imaging – denosumab – bisphosphonates
Authors: Řehák Zdeněk, Ptáčník Václav, Adam Zdeněk, Koukalová Renata, Straub Jan, Křiva Tomáš, Adamová Zuzana, Křivanová Andrea, Boichuk Ivanna, Pour Luděk2026-08-15:Contribution of bone scintigraphy and PET/CT in the differential diagnosis of bone involvement in a patient with fibrous dysplasia and monoclonal gammopathy of undetermined significance and fibrous dysplasia treatment with denosumab
Keywords: fibrous dysplasia – monoclonal gammopathy of undetermined significance – MGUS – PET/CT imaging – denosumab – bisphosphonates
Authors: Řehák Zdeněk, Ptáčník Václav, Adam Zdeněk, Koukalová Renata, Straub Jan, Křiva Tomáš, Adamová Zuzana, Křivanová Andrea, Boichuk Ivanna, Pour Luděk2026-08-15:Contribution of bone scintigraphy and PET/CT in the differential diagnosis of bone involvement in a patient with fibrous dysplasia and monoclonal gammopathy of undetermined significance and fibrous dysplasia treatment with denosumab
Onkology in pictures
Klin Onkol 2026; 39(4): 302-304.
DOI: 10.48095/ccko2026302.
Keywords: 18F-FDG-PET/CT
Authors: Řehák Zdeněk, Adam Zdeněk, Horváth Teodor, Vašina Jiří, Koukalová Renata, Fabián Pavel, Adam Jan2026-08-15:18F-FDG-PET/CT in the diagnosis of lymphadenopathy
Keywords: 18F-FDG-PET/CT
Authors: Řehák Zdeněk, Adam Zdeněk, Horváth Teodor, Vašina Jiří, Koukalová Renata, Fabián Pavel, Adam Jan2026-08-15:18F-FDG-PET/CT in the diagnosis of lymphadenopathy