Klin Onkol 2026; 39(Suppl 1): 31-35. DOI: 10.48095/ccko2026S31.
Smoking is responsible for approximately 25–30% of all oncological diseases. The link with lung cancer, which is the strongest, and is therefore well known, has been demonstrated first. Unfortunately, smoking also contributes to other types of cancer, practically all kinds except endometrial cancer. However, due to the carcinogenic and other toxic effects of several thousand substances in tobacco smoke, smoking has been increasingly replaced in recent years by smoke-free forms of nicotine. Nicotine itself is not carcinogenic; on the contrary, some forms of nicotine replacement therapy are among the World Health Organization‘s essential medicines.