Methodological problems of clinical trials in oncology

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Klin Onkol 2005; 18(Suppl 2005): 252-255.

Summary: Randomized clinical trials are considered to be one of the most important tools, that allow direct comparison of current standard and experimental therapies. Subsequently, the more efficient and/or better tolerated regimen is selected as the new standard. This article focuses on the problems with the interpretation of trial results as well as on the use of these trials in the selection of appropriate therapies for the individual patient.

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