Klin Onkol 2016; 29(3): 196-203. DOI: 10.14735/amko2016196.

Background: Pancreatic cancer is serious and rapidly progressing condition. Little is known about the role of diet in etiology of pancreatic cancer. The study focused on the role of selected dietary factors related to pancreatic cancer. Material and Methods: The case-control study was performed in the Czech Republic in 2006– 2009, involving three centers in Olomouc, Ostrava and Ceske Budejovice. It comprised a total of 530 persons, of whom 310 had pancreatic cancer and 220 were controls. Data were obtained directly from each participant in an interview with a trained interviewer and entered into a standardized questionnaire. The data were analyzed using a crude odds ratio (OR) and multivariate logistic regression with an adjusted OR and 95% CI. The statistical analysis was performed
with the STATA v. 10 software. Results: A very strong protective eff ect was found in pickled cabbage (OR 0.32; 95% CI 0.19– 0.55), broccoli (OR 0.37; 95% CI 0.25– 0.53), cooked onion (OR 0.14; 95% CI 0.08– 0.27), tomatoes (OR 0.28; 95% CI 0.13– 0.60), raw carrot (OR 0.33; 95% CI 0.20– 0.56), cooked carrot (OR 0.35; 95% CI 0.19– 0.62). In logistic regression model, statistically signifi cant protective associations were found in consumption of more than three portions of cooked vegetables per week (OR 0.16; 95% CI 0.05– 0.55) and high consumption of citrus fruit (OR 0.46; 95% CI 0.23– 0.90). Conclusion: The study found statistically signifi cant protective eff ect of consumption of more than three portions of cooked vegetables per week and high consumption of citrus fruit.


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