Impact of Treatments to Improve Cognitive Function and Quality of Life on Cancer Patients with Carcinoma of the Testes


Klin Onkol 2016; 29(4): 267-273. DOI: 10.14735/amko2016267.

Background: Testicular cancer is one of the most common and most treatable cancers in men aged 15–49 years. The high survival rates mean that it is essential to maintain quality of life and minimize adverse eff ects associated with treatment. Both malignant tumors and the
modalities used to treatment them can have adverse eff ects from both a psychosocial and a neurocognitive function perspective. Recently, attention has focused on the negative impact of the disease and its treatment on the brain and on cognitive function, which can result in
a form of neurocognitive dysfunction known as „chemo brain“ or „chemo fog“. Both cancer itself and the modalities used to treat it are associated with neurotoxicity and cognitive defi cit, which are manifest in key areas of cognitive function. These problems may adversely affect both patients undergoing treatment and those in remission, with a consequent reduction in quality of life. Because many patients survive testicular cancer, it is important to understand the characteristics, range, and time course of disease symptoms, treatment, and side effects, all of which can lead to long-term physical, psychological, and social problems. Testicular cancer has a high potential for cure; therefore, patients suff er not only short-term but also long-term side eff ects associated with therapy. Aims: This article aims to off er a complete and concise overview of cognitive dysfunction and quality of life for patients with testicular cancer. Conclusion: It would be beneficial if research into testicular cancer also focused on the relationships between psychosocial factors, psychological disorders, and cognitive function.

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