Klin Onkol 2019; 32(Suppl 3): 19-24.
DOI: 10.14735/amko20193S19.
Keywords: synthetic lethality – PARP inhibitors – olaparib – BRCAness – DNA repair
Authors: Bortlíková Lucie, Müller Petr, Vojtěšek Bořivoj, Rak Vladimír, Svoboda Marek2019-10-14:Synthetic Lethality – Its Current Application and Potential in Oncological Treatment
Keywords: synthetic lethality – PARP inhibitors – olaparib – BRCAness – DNA repair
Authors: Bortlíková Lucie, Müller Petr, Vojtěšek Bořivoj, Rak Vladimír, Svoboda Marek2019-10-14:Synthetic Lethality – Its Current Application and Potential in Oncological Treatment
Klin Onkol 2019; 32(Suppl 3): 25-33.
DOI: 10.14735/amko20193S25.
Keywords: cancer – chemotherapy – drugs – organometallic compounds – titanium – ruthenium
Authors: Skoupilová Hana, Hrstka Roman2019-10-14:Progress in the Utilisation of Organometallic Compounds in the Development of Cancer Drugs
Keywords: cancer – chemotherapy – drugs – organometallic compounds – titanium – ruthenium
Authors: Skoupilová Hana, Hrstka Roman2019-10-14:Progress in the Utilisation of Organometallic Compounds in the Development of Cancer Drugs
Klin Onkol 2019; 32(Suppl 3): 34-38.
DOI: 10.14735/amko20193S34.
Keywords: signal transduction – breast neoplasms – oestrogen receptors
Authors: Voňka Petr, Hrstka Roman2019-10-14:Overview of Current Findings about the Role of Oestrogen Receptor α in Cancer Cell Signalling Pathways
Keywords: signal transduction – breast neoplasms – oestrogen receptors
Authors: Voňka Petr, Hrstka Roman2019-10-14:Overview of Current Findings about the Role of Oestrogen Receptor α in Cancer Cell Signalling Pathways
Klin Onkol 2019; 32(Suppl 3): 39-45.
DOI: 10.14735/amko20193S39.
Keywords: glycoproteins – serum – biomarkers – cancer
Authors: Hernychová Lenka, Uhrík Lukáš, Nenutil Rudolf, Novotný Miloš2019-10-14:Glycoproteins in the Sera of Oncological Patients
Keywords: glycoproteins – serum – biomarkers – cancer
Authors: Hernychová Lenka, Uhrík Lukáš, Nenutil Rudolf, Novotný Miloš2019-10-14:Glycoproteins in the Sera of Oncological Patients
Klin Onkol 2019; 32(Suppl 3): 46-55.
DOI: 10.14735/amko20193S46.
Keywords: antibodies – glycosylation – pharmacology – immune system – therapeutics
Authors: Uhrík Lukáš, Hernychová Lenka, Vojtěšek Bořivoj2019-10-14:Glycosylation as an Important Regulator of Antibody Function
Keywords: antibodies – glycosylation – pharmacology – immune system – therapeutics
Authors: Uhrík Lukáš, Hernychová Lenka, Vojtěšek Bořivoj2019-10-14:Glycosylation as an Important Regulator of Antibody Function
Klin Onkol 2019; 32(Suppl 3): 56-64.
DOI: 10.14735/amko20193S56.
Keywords: ubiquitin – mass spectrometry – neoplasms – proteins – proteomics
Authors: Faktor Jakub, Pjechová Mariana, Hernychová Lenka, Vojtěšek Bořivoj2019-10-14:Protein Ubiquitination Research in Oncology
Keywords: ubiquitin – mass spectrometry – neoplasms – proteins – proteomics
Authors: Faktor Jakub, Pjechová Mariana, Hernychová Lenka, Vojtěšek Bořivoj2019-10-14:Protein Ubiquitination Research in Oncology
Klin Onkol 2019; 32(Suppl 3): 65-71.
DOI: 10.14735/amko20193S65.
Keywords: long non-coding RNA – tumor biomarkers – carcinogenesis – biosensing techniques
Authors: Moráňová Ludmila, Bartošík Martin2019-10-14:Long Non-Coding RNAs – Current Methods of Detection and Clinical Applications
Keywords: long non-coding RNA – tumor biomarkers – carcinogenesis – biosensing techniques
Authors: Moráňová Ludmila, Bartošík Martin2019-10-14:Long Non-Coding RNAs – Current Methods of Detection and Clinical Applications
Klin Onkol 2019; 32(Suppl 3): 72-77.
DOI: 10.14735/amko20193S72.
Keywords: viry – virové proteiny – p53 – p63 – p73 – tumorigeneze
Authors: Brychtová Veronika, Hrabal Václav, Vojtěšek Bořivoj2019-10-14:Oncogenic Viral Protein Interactions with p53 Family Proteins
Keywords: viry – virové proteiny – p53 – p63 – p73 – tumorigeneze
Authors: Brychtová Veronika, Hrabal Václav, Vojtěšek Bořivoj2019-10-14:Oncogenic Viral Protein Interactions with p53 Family Proteins
Klin Onkol 2019; 32(Suppl 3): 78-85.
DOI: 10.14735/amko20193S78.
Keywords: genomics – transcriptomics – proteomics – bioinformatics – software development
Authors: Zavadil Kokáš Filip, Faktor Jakub, Vojtěšek Bořivoj2019-10-14:Cooperation of Genomic, Transcriptomics and Proteomic Methods in the Detection of Mutated Proteins
Keywords: genomics – transcriptomics – proteomics – bioinformatics – software development
Authors: Zavadil Kokáš Filip, Faktor Jakub, Vojtěšek Bořivoj2019-10-14:Cooperation of Genomic, Transcriptomics and Proteomic Methods in the Detection of Mutated Proteins
Klin Onkol 2019; 32(Suppl 2): 6-13.
DOI: 10.14735/amko2019S6.
Keywords: genes – BRCA1 – BRCA2 – genetic testing – prophylactic mastectomy – salpingo-oophorectomy – high-throughput nucleotide sequencing
Authors: Foretová Lenka, Navrátilová Marie, Svoboda Marek, Vašíčková Petra, Sťahlová Hrabincová Eva, Házová Jana, Kleiblová Petra, Kleibl Zdeněk, Macháčková Eva, Palácová Markéta, Petráková Katarína2019-08-18:Recommendations for Preventive Care for Women with Rare Genetic Cause of Breast and Ovarian Cancer
Keywords: genes – BRCA1 – BRCA2 – genetic testing – prophylactic mastectomy – salpingo-oophorectomy – high-throughput nucleotide sequencing
Authors: Foretová Lenka, Navrátilová Marie, Svoboda Marek, Vašíčková Petra, Sťahlová Hrabincová Eva, Házová Jana, Kleiblová Petra, Kleibl Zdeněk, Macháčková Eva, Palácová Markéta, Petráková Katarína2019-08-18:Recommendations for Preventive Care for Women with Rare Genetic Cause of Breast and Ovarian Cancer
Klin Onkol 2019; 32(Suppl 2): 14-23.
DOI: 10.14735/amko2019S14.
Keywords: hereditary cancer syndromes – autozomal recessive inheritance – heterozygote – mutation – risk of cancer – predictive testing
Authors: Koudová Monika, Puchmajerová Alena2019-08-18:Risks of Solid Tumors in Heterozygous Carriers of Recessive Syndromes
Keywords: hereditary cancer syndromes – autozomal recessive inheritance – heterozygote – mutation – risk of cancer – predictive testing
Authors: Koudová Monika, Puchmajerová Alena2019-08-18:Risks of Solid Tumors in Heterozygous Carriers of Recessive Syndromes
Klin Onkol 2019; 32(Suppl 2): 23-27.
DOI: 10.14735/amko2019S23.
Keywords: genetic testing – hereditary cancer syndromes – DICER1 – pleuropulmonary blastoma – cystic nephroma
Authors: Hořínová Věra, Drábová Klára, Nosková Hana, Bajčiová Viera, Šoukalová Jana, Černá Leona, Hůrková Věra, Slabý Ondřej, Štěrba Jaroslav2019-08-18:DICER1 Syndrome
Keywords: genetic testing – hereditary cancer syndromes – DICER1 – pleuropulmonary blastoma – cystic nephroma
Authors: Hořínová Věra, Drábová Klára, Nosková Hana, Bajčiová Viera, Šoukalová Jana, Černá Leona, Hůrková Věra, Slabý Ondřej, Štěrba Jaroslav2019-08-18:DICER1 Syndrome
Klin Onkol 2019; 32(Suppl 2): 24-30.
DOI: 10.14735/amko2019S24.
Keywords: breast cancer – BRCA1/2 mutation – genomic tests – platinum salts – PARP inhibitors
Authors: Palácová Markéta2019-08-18:Breast Cancer in BRCA1/2 Mutation Carriers – Do We Treat It Differently? Focus on Systemic Therapy for BRCA1/2 Associated Breast Cancer
Keywords: breast cancer – BRCA1/2 mutation – genomic tests – platinum salts – PARP inhibitors
Authors: Palácová Markéta2019-08-18:Breast Cancer in BRCA1/2 Mutation Carriers – Do We Treat It Differently? Focus on Systemic Therapy for BRCA1/2 Associated Breast Cancer
Klin Onkol 2019; 32(Suppl 2): 31-35.
DOI: 10.14735/amko2019S31.
Keywords: breast cancer – genes, BRCA1 – genes, BRCA2 – neoadjuvant therapy – cisplatin – carboplatin – pathologic complete response
Authors: Holánek Miloš, Bílek Ondřej, Nenutil Rudolf, Kazda Tomáš, Selingerová Iveta, Zvaríková Mária, Palácová Markéta, Vyzula Rostislav, Petráková Katarína2019-08-18:Effectiveness of Neoadjuvant Therapy with Platinum-Based Agents for Patients with BRCA1 and BRCA2 Germline Mutations – A Retrospective Analysis of Breast Cancer Patients Treated at MMCI Brno
Keywords: breast cancer – genes, BRCA1 – genes, BRCA2 – neoadjuvant therapy – cisplatin – carboplatin – pathologic complete response
Authors: Holánek Miloš, Bílek Ondřej, Nenutil Rudolf, Kazda Tomáš, Selingerová Iveta, Zvaríková Mária, Palácová Markéta, Vyzula Rostislav, Petráková Katarína2019-08-18:Effectiveness of Neoadjuvant Therapy with Platinum-Based Agents for Patients with BRCA1 and BRCA2 Germline Mutations – A Retrospective Analysis of Breast Cancer Patients Treated at MMCI Brno
Klin Onkol 2019; 32(Suppl 2): 36-50.
DOI: 10.14735/amko2019S36.
Keywords: breast cancer – CHEK2 – hereditary mutations – variants of unknown significance – functional analysis
Authors: Kleiblová Petra, Stolařová Lenka, Křížová Kateřina, Lhota Filip, Hojný Jan, Zemánková Petra, Havránek Ondřej, Vočka Michal, Černá Marta, Lhotová Klára, Borecká Marianna, Janatová Markéta, Soukupová Jana, Ševčík Jan, Zimovjanová Martina, Kotlas Jaroslav, Panczak Aleš, Veselá Kamila, Červenková Jana, Schneiderová Michaela, Burócziová Monika, Burdová Kamila, Stránecký Viktor, Foretová Lenka, Macháčková Eva, Tavandzis Spiros, Kmoch Stanislav, Macůrek Libor, Kleibl Zdeněk2019-08-18:Germline CHEK2 Gene Mutations in Hereditary Breast Cancer Predisposition – Mutation Types and their Biological and Clinical Relevance
Keywords: breast cancer – CHEK2 – hereditary mutations – variants of unknown significance – functional analysis
Authors: Kleiblová Petra, Stolařová Lenka, Křížová Kateřina, Lhota Filip, Hojný Jan, Zemánková Petra, Havránek Ondřej, Vočka Michal, Černá Marta, Lhotová Klára, Borecká Marianna, Janatová Markéta, Soukupová Jana, Ševčík Jan, Zimovjanová Martina, Kotlas Jaroslav, Panczak Aleš, Veselá Kamila, Červenková Jana, Schneiderová Michaela, Burócziová Monika, Burdová Kamila, Stránecký Viktor, Foretová Lenka, Macháčková Eva, Tavandzis Spiros, Kmoch Stanislav, Macůrek Libor, Kleibl Zdeněk2019-08-18:Germline CHEK2 Gene Mutations in Hereditary Breast Cancer Predisposition – Mutation Types and their Biological and Clinical Relevance