Klin Onkol 2026; 39(4): 276-286.
DOI: 10.48095/ccko2026276.
Keywords: cryotherapy – freezing – imaging, three-dimensional – ice ball –size
Authors: de Palma Angelica, Cortese Francesco, Di Giovanni Giuseppe, Acquafredda Fabrizio, Pisani Antonio Rosario, Inchingolo Riccardo2026-08-15:Evaluation of ice ball size as a function of freezing intensity through computed tomography scans during cryoablation procedures
Keywords: cryotherapy – freezing – imaging, three-dimensional – ice ball –size
Authors: de Palma Angelica, Cortese Francesco, Di Giovanni Giuseppe, Acquafredda Fabrizio, Pisani Antonio Rosario, Inchingolo Riccardo2026-08-15:Evaluation of ice ball size as a function of freezing intensity through computed tomography scans during cryoablation procedures
Klin Onkol 2026; 39(4): 287-293.
DOI: 10.48095/ccko2026287.
Keywords: non-small-cell lung carcinoma – next-generation sequencing – FGFR2 fusion – pemigatinib – pancreatobiliary adenocarcinoma
Authors: Pešek Miloš, Drösslerová Marie, Vaněček Tomáš, Bocko Jozef 2026-08-15:FGFR2 fusion as the key to targeted therapy – a case report with a diagnostic turning point
Keywords: non-small-cell lung carcinoma – next-generation sequencing – FGFR2 fusion – pemigatinib – pancreatobiliary adenocarcinoma
Authors: Pešek Miloš, Drösslerová Marie, Vaněček Tomáš, Bocko Jozef 2026-08-15:FGFR2 fusion as the key to targeted therapy – a case report with a diagnostic turning point
Klin Onkol 2026; 39(4): 294-301.
DOI: 10.48095/ccko2026294.
Keywords: fibrous dysplasia – monoclonal gammopathy of undetermined significance – MGUS – PET/CT imaging – denosumab – bisphosphonates
Authors: Řehák Zdeněk, Ptáčník Václav, Adam Zdeněk, Koukalová Renata, Straub Jan, Křiva Tomáš, Adamová Zuzana, Křivanová Andrea, Boichuk Ivanna, Pour Luděk2026-08-15:Contribution of bone scintigraphy and PET/CT in the differential diagnosis of bone involvement in a patient with fibrous dysplasia and monoclonal gammopathy of undetermined significance and fibrous dysplasia treatment with denosumab
Keywords: fibrous dysplasia – monoclonal gammopathy of undetermined significance – MGUS – PET/CT imaging – denosumab – bisphosphonates
Authors: Řehák Zdeněk, Ptáčník Václav, Adam Zdeněk, Koukalová Renata, Straub Jan, Křiva Tomáš, Adamová Zuzana, Křivanová Andrea, Boichuk Ivanna, Pour Luděk2026-08-15:Contribution of bone scintigraphy and PET/CT in the differential diagnosis of bone involvement in a patient with fibrous dysplasia and monoclonal gammopathy of undetermined significance and fibrous dysplasia treatment with denosumab
Klin Onkol 2026; 39(4): 302-304.
DOI: 10.48095/ccko2026302.
Keywords: 18F-FDG-PET/CT
Authors: Řehák Zdeněk, Adam Zdeněk, Horváth Teodor, Vašina Jiří, Koukalová Renata, Fabián Pavel, Adam Jan2026-08-15:18F-FDG-PET/CT in the diagnosis of lymphadenopathy
Keywords: 18F-FDG-PET/CT
Authors: Řehák Zdeněk, Adam Zdeněk, Horváth Teodor, Vašina Jiří, Koukalová Renata, Fabián Pavel, Adam Jan2026-08-15:18F-FDG-PET/CT in the diagnosis of lymphadenopathy
Klin Onkol 2026; 39(3): 150-168.
DOI: 10.48095/ccko2026150.
Keywords: histiocytosis
Authors: Adam Zdeněk, Eid Michal, Řehák Zdeněk, Kubeš Václav , Horváth Teodor, Doubková Martina, Starý Karel, Šlampa Pavel, Čermák Aleš, Fadrus Pavel, Adamová Zuzana, Vaníček Jiří, Nebeský Tomáš, Kamarádová Kateřina, Boichuk Ivanna, Pour Luděk2026-06-15:Clinical presentations of the most common histiocytic disorders
Keywords: histiocytosis
Authors: Adam Zdeněk, Eid Michal, Řehák Zdeněk, Kubeš Václav , Horváth Teodor, Doubková Martina, Starý Karel, Šlampa Pavel, Čermák Aleš, Fadrus Pavel, Adamová Zuzana, Vaníček Jiří, Nebeský Tomáš, Kamarádová Kateřina, Boichuk Ivanna, Pour Luděk2026-06-15:Clinical presentations of the most common histiocytic disorders
Klin Onkol 2026; 39(3): 169-183.
DOI: 10.48095/ccko2026169.
Keywords: Castleman disease
Authors: Adam Zdeněk, Kamarádová Kateřina, Doubková Martina, Řehák Zdeněk, Koukalová Renata, Křivanová Andrea, Horváth Teodor, Čermák Aleš, Boichuk Ivanna, Štork Martin, Sandecká Viera, Adamová Zuzana, Pour Luděk2026-06-15:Chronic low-grade fever or fever with mild lymphadenopathy may indicate Castleman disease if no malignant, autoimmune, or infectious cause of the lymphadenopathy is identified
Keywords: Castleman disease
Authors: Adam Zdeněk, Kamarádová Kateřina, Doubková Martina, Řehák Zdeněk, Koukalová Renata, Křivanová Andrea, Horváth Teodor, Čermák Aleš, Boichuk Ivanna, Štork Martin, Sandecká Viera, Adamová Zuzana, Pour Luděk2026-06-15:Chronic low-grade fever or fever with mild lymphadenopathy may indicate Castleman disease if no malignant, autoimmune, or infectious cause of the lymphadenopathy is identified
Klin Onkol 2026; 39(3): 184-194.
DOI: 10.48095/ccko2026184.
Keywords: endometrial cancer – systemic treatment – chemotherapy – immunotherapy – second and subsequent lines of therapy – pembrolizumab – lenvatinib
Authors: Bednaříková Markéta, Koblížková Michaela, Ovesná Petra, Hausnerová Jitka, Ehrlichová Lucie, Felsinger Michal , Tomková Martina, Minář Luboš, Weinberger Vít2026-06-15:Second and subsequent lines of systemic therapy in endometrial cancer – a real-life clinical experience
Keywords: endometrial cancer – systemic treatment – chemotherapy – immunotherapy – second and subsequent lines of therapy – pembrolizumab – lenvatinib
Authors: Bednaříková Markéta, Koblížková Michaela, Ovesná Petra, Hausnerová Jitka, Ehrlichová Lucie, Felsinger Michal , Tomková Martina, Minář Luboš, Weinberger Vít2026-06-15:Second and subsequent lines of systemic therapy in endometrial cancer – a real-life clinical experience
Klin Onkol 2026; 39(3): 195-198.
DOI: 10.48095/ccko2026195.
Keywords: cholangiocarcinoma – targeted therapy – pemigatinib – FGFR tyrosine kinase inhibitor
Authors: Bohuňovská Kateřina2026-06-15:From progression to complete remission – a case study of successful pemigatinib treatment in a patient with metastatic FGFR2+ cholangiocarcinoma
Keywords: cholangiocarcinoma – targeted therapy – pemigatinib – FGFR tyrosine kinase inhibitor
Authors: Bohuňovská Kateřina2026-06-15:From progression to complete remission – a case study of successful pemigatinib treatment in a patient with metastatic FGFR2+ cholangiocarcinoma
Klin Onkol 2026; 39(3): 199-211.
DOI: 10.48095/ccko2026199.
Keywords: Erdheim-Chester disease – FDG-PET/CT – NaF-PET/CT – skeletal scintigraphy – anakinra – cladribine
Authors: Řehák Zdeněk, Stejskal Václav, Adam Zdeněk, Kamarádová Kateřina, Štěpánková Pavla, Soboličová Sandra, Ošmera Pavel, Starý Karel, Nehyba Svatopluk, Čermák Aleš, Standara Michal, Pour Luděk2026-06-15:Differences in the imaging of Erdheim-Chester disease using FDG-PET/CT, NaF-PET/CT examinations, and skeletal scintigraphy. Regression of the disease after treatment with cladribine combined with cyclophosphamide and anakinra
Keywords: Erdheim-Chester disease – FDG-PET/CT – NaF-PET/CT – skeletal scintigraphy – anakinra – cladribine
Authors: Řehák Zdeněk, Stejskal Václav, Adam Zdeněk, Kamarádová Kateřina, Štěpánková Pavla, Soboličová Sandra, Ošmera Pavel, Starý Karel, Nehyba Svatopluk, Čermák Aleš, Standara Michal, Pour Luděk2026-06-15:Differences in the imaging of Erdheim-Chester disease using FDG-PET/CT, NaF-PET/CT examinations, and skeletal scintigraphy. Regression of the disease after treatment with cladribine combined with cyclophosphamide and anakinra
Klin Onkol 2026; 39(3): 212-214.
DOI: 10.48095/ccko2026212.
Authors: Řehák Zdeněk, Brychta Jindřich, Bencsiková Beatrix, Hendrych Michal, Balážová Zuzana, Jančálek Radim2026-06-15:68Ga-DOTATOC PET/CT – a case report of synchronous oncological duplicity with high expression of somatostatin receptors
Authors: Řehák Zdeněk, Brychta Jindřich, Bencsiková Beatrix, Hendrych Michal, Balážová Zuzana, Jančálek Radim2026-06-15:68Ga-DOTATOC PET/CT – a case report of synchronous oncological duplicity with high expression of somatostatin receptors
Klin Onkol 2026; 39(2): 86-98.
DOI: 10.48095/ccko202686.
Keywords: Castleman disease – siltuximab – rituximab – anakinra – ruxolitinib – sirolimus – rapamycin – daratumab – bortezomib
Authors: Adam Zdeněk, Řehák Zdeněk, Boichuk Ivanna, Horváth Teodor, Adamová Zuzana, Štork Martin, Pour Luděk2026-04-15:Treatment of Castleman disease from the perspective of the year 2026
Keywords: Castleman disease – siltuximab – rituximab – anakinra – ruxolitinib – sirolimus – rapamycin – daratumab – bortezomib
Authors: Adam Zdeněk, Řehák Zdeněk, Boichuk Ivanna, Horváth Teodor, Adamová Zuzana, Štork Martin, Pour Luděk2026-04-15:Treatment of Castleman disease from the perspective of the year 2026
Klin Onkol 2026; 39(2): 99-104.
DOI: 10.48095/ccko202699.
Keywords: Ewing sarcoma – chemotherapy – targeted therapy
Authors: Nohejlová-Medková Anna, Pacas Pavel, Kopečková Kateřina2026-04-15:Ewing sarcoma – current diagnostic and therapeutic approaches
Keywords: Ewing sarcoma – chemotherapy – targeted therapy
Authors: Nohejlová-Medková Anna, Pacas Pavel, Kopečková Kateřina2026-04-15:Ewing sarcoma – current diagnostic and therapeutic approaches
Klin Onkol 2026; 39(2): 105-111.
DOI: 10.48095/ccko2026105.
Keywords: colorectal cancer – circulating tumor DNA – minimal residual disease – adjuvant chemotherapy – liquid biopsy – personalized oncology
Authors: Pirshtuk Alina, Büchler Tomáš, Vymetálková Veronika2026-04-15:Circulating tumor DNA as a biomarker for the prediction of minimal residual disease and the individualization of adjuvant therapy in colorectal cancer – a review of current evidence and perspectives
Keywords: colorectal cancer – circulating tumor DNA – minimal residual disease – adjuvant chemotherapy – liquid biopsy – personalized oncology
Authors: Pirshtuk Alina, Büchler Tomáš, Vymetálková Veronika2026-04-15:Circulating tumor DNA as a biomarker for the prediction of minimal residual disease and the individualization of adjuvant therapy in colorectal cancer – a review of current evidence and perspectives
Klin Onkol 2026; 39(2): 112-116.
DOI: 10.48095/ccko2026112.
Keywords: leiomyomatosis – adenomyosis – fumarate hydratase – intravascular propagation
Authors: Bartoš Vladimír, Hudec Boris, Baloghová Erika2026-04-15:Intravascular propagation of adenomyosis within the blood vessels of the myometrium and uterine leiomyoma in a patient harboring germline mutation in the fumarate hydratase gene – a rare finding simulating malignancy
Keywords: leiomyomatosis – adenomyosis – fumarate hydratase – intravascular propagation
Authors: Bartoš Vladimír, Hudec Boris, Baloghová Erika2026-04-15:Intravascular propagation of adenomyosis within the blood vessels of the myometrium and uterine leiomyoma in a patient harboring germline mutation in the fumarate hydratase gene – a rare finding simulating malignancy
Klin Onkol 2026; 39(2): 117-121.
DOI: 10.48095/ccko2026117.
Keywords: breast cancer – late recurrence – second recurrence
Authors: Maezawa Yosuke, Terada Takeshi, Kobayashi Hiroyuki, Ohara Gen, Saito Takeshi, Takayashiki Norio, Satoh Hiroaki2026-04-15:Second recurrence of breast cancer 36 years after initial surgery and 18 years after the first recurrence – an extremely rare case
Keywords: breast cancer – late recurrence – second recurrence
Authors: Maezawa Yosuke, Terada Takeshi, Kobayashi Hiroyuki, Ohara Gen, Saito Takeshi, Takayashiki Norio, Satoh Hiroaki2026-04-15:Second recurrence of breast cancer 36 years after initial surgery and 18 years after the first recurrence – an extremely rare case