Klin Onkol 2025; 38(5): 390-397.
DOI: 10.48095/ccko2025390.
Keywords: multiple myeloma – precision medicine – BRAF inhibitors – next-generation sequencing
Authors: Štork Martin, Kotašková Jana, Ondroušková Eva, Borský Marek, Marečková Andrea, Sendlerová Nela, Mayerová Johana, Brada Michal, Boichuk Ivanna, Menšíková Klára, Adam Zdeněk, Krejčí Marta, Sandecká Viera, Jelínková Zuzana, Krtička Milan, Nekuda Vladimír, Bilčíková Michaela, Hrabčáková Viera, Vojtková Lenka , Jarošová Marie, Šlampa Pavel, Pour Luděk2025-10-15:Precision medicine in hemato-oncology – treatment of refractory multiple myeloma with massive extramedullary involvement using BRAF/MEK inhibitors
Keywords: multiple myeloma – precision medicine – BRAF inhibitors – next-generation sequencing
Authors: Štork Martin, Kotašková Jana, Ondroušková Eva, Borský Marek, Marečková Andrea, Sendlerová Nela, Mayerová Johana, Brada Michal, Boichuk Ivanna, Menšíková Klára, Adam Zdeněk, Krejčí Marta, Sandecká Viera, Jelínková Zuzana, Krtička Milan, Nekuda Vladimír, Bilčíková Michaela, Hrabčáková Viera, Vojtková Lenka , Jarošová Marie, Šlampa Pavel, Pour Luděk2025-10-15:Precision medicine in hemato-oncology – treatment of refractory multiple myeloma with massive extramedullary involvement using BRAF/MEK inhibitors
Klin Onkol 2025; 38(Suppl 1): 104-107.
DOI: 10.48095/ccko2025104.
Keywords: breast cancer – chemoprevention – phytopharmaceutical – epigenetics
Authors: Kapinová Andrea, Kašubová Ivana, Šarlinová Miroslava, Mazuráková Alena, Dvorská Dana, Braný Dušan, Danková Zuzana, Kajo Karol, Kubatka Peter2025-08-31:Antitumor potential of whole plant functional foods in breast cancer
Keywords: breast cancer – chemoprevention – phytopharmaceutical – epigenetics
Authors: Kapinová Andrea, Kašubová Ivana, Šarlinová Miroslava, Mazuráková Alena, Dvorská Dana, Braný Dušan, Danková Zuzana, Kajo Karol, Kubatka Peter2025-08-31:Antitumor potential of whole plant functional foods in breast cancer
Klin Onkol 2025; 38(Suppl 1): 108-113.
DOI: 10.48095/ccko2025108.
Keywords: interpretative phenomenological analysis – cancer – quality of life – life changes – psychosocial intervention – secondary losses – disease trajectory
Authors: Klepáčková Olga, Tomka Milan2025-08-31:Experiencing secondary losses in cancer patients concerning disease trajectory
Keywords: interpretative phenomenological analysis – cancer – quality of life – life changes – psychosocial intervention – secondary losses – disease trajectory
Authors: Klepáčková Olga, Tomka Milan2025-08-31:Experiencing secondary losses in cancer patients concerning disease trajectory
Klin Onkol 2025; 38(4): 254-263.
DOI: 10.48095/ccko2025254.
Keywords: human cytomegalovirus – glioblastoma – antiviral therapy – immunohistochemistry – clinical diagnostics
Authors: Fried Aneta , Strmisková Johana, Magerová Kateřina , Hendrych Michal, Bartošík Martin, Moráňová Ludmila2025-08-15:Impact and detection of human cytomegalovirus in oncological diseases
Keywords: human cytomegalovirus – glioblastoma – antiviral therapy – immunohistochemistry – clinical diagnostics
Authors: Fried Aneta , Strmisková Johana, Magerová Kateřina , Hendrych Michal, Bartošík Martin, Moráňová Ludmila2025-08-15:Impact and detection of human cytomegalovirus in oncological diseases
Klin Onkol 2025; 38(4): 264-269.
DOI: 10.48095/ccko2025264.
Keywords: integrative medicine – complementary and alternative medicine – oncology care – quality of life – placebo effect – patient-centered care
Authors: Světlák Miroslav2025-08-15:Integrative medicine in oncology – between science, ideology, and pragmatism
Keywords: integrative medicine – complementary and alternative medicine – oncology care – quality of life – placebo effect – patient-centered care
Authors: Světlák Miroslav2025-08-15:Integrative medicine in oncology – between science, ideology, and pragmatism
Klin Onkol 2025; 38(4): 270-281.
DOI: 10.48095/ccko2025270.
Keywords: TUDCA – tauroursodeoxycholic acid – endoplasmic reticulum stress – liver diseases – metabolic diseases – neurodegenerative diseases – immune function – cancer
Authors: Vavrušáková Barbora, Bartošová Renata, Svoboda Marek, Moráň Lukáš2025-08-15:From traditional Chinese medicine to molecular oncology – pleiotropic effects of tauroursodeoxycholic acid
Keywords: TUDCA – tauroursodeoxycholic acid – endoplasmic reticulum stress – liver diseases – metabolic diseases – neurodegenerative diseases – immune function – cancer
Authors: Vavrušáková Barbora, Bartošová Renata, Svoboda Marek, Moráň Lukáš2025-08-15:From traditional Chinese medicine to molecular oncology – pleiotropic effects of tauroursodeoxycholic acid
Klin Onkol 2025; 38(4): 283-301.
DOI: 10.48095/ccko2025283.
Keywords: TEMPI syndrome – telangiectasia – erythrocytosis – monoclonal gammopathy – perinephritic fluid collection – intrapulmonary arteriovenous shunts – Waldenström‘s macroglobulinemia – monoclonal gammopathy of clinical significance – venous thrombosis
Authors: Adam Zdeněk, Leová Lan Ngoc, Patočková Miroslava, Rajecká Silvia, Nehyba Svatopluk, Borský Marek, Kotašková Jana, Kubeš Václav , Kissová Jaroslava, Vaníček Jiří, Pazdičová Zuzana , Řehák Zdeněk, Foukal Jakub, Čermák Aleš, Adamová Zuzana, Zdražilová Dubská Lenka, Starý Karel, Boichuk Ivanna, Pour Luděk2025-08-15:Description of TEMPI syndrome in Waldenström‘s macroglobulinemia
Keywords: TEMPI syndrome – telangiectasia – erythrocytosis – monoclonal gammopathy – perinephritic fluid collection – intrapulmonary arteriovenous shunts – Waldenström‘s macroglobulinemia – monoclonal gammopathy of clinical significance – venous thrombosis
Authors: Adam Zdeněk, Leová Lan Ngoc, Patočková Miroslava, Rajecká Silvia, Nehyba Svatopluk, Borský Marek, Kotašková Jana, Kubeš Václav , Kissová Jaroslava, Vaníček Jiří, Pazdičová Zuzana , Řehák Zdeněk, Foukal Jakub, Čermák Aleš, Adamová Zuzana, Zdražilová Dubská Lenka, Starý Karel, Boichuk Ivanna, Pour Luděk2025-08-15:Description of TEMPI syndrome in Waldenström‘s macroglobulinemia
Klin Onkol 2025; 38(4): 302-306.
DOI: 10.48095/ccko2025302.
Keywords: retroperitoneal metastasis – lymph node metastasis – leiomyosarcoma – sternum – minimally invasive metastasectomy – adrenalectomy
Authors: Ioannidis Orestis, Kotidis Efstathios, Anestiadou Elissavet, Matzarakis Ioannis, Skliris James Philip, Symeonidis Savvas, Bitsianis Stefanos, Kerasidou Ourania, Kaprianou Magda, Chatzianestiadou Christiana, Salta-Poupnara Eleni, Tserkezidis Freiderikos, Angelopolos Konstantinos, Angelopoulos Stamatios2025-08-15:Laparoscopic resection of retroperitoneal metastasis originating from sternal leiomyosarcoma – a case report
Keywords: retroperitoneal metastasis – lymph node metastasis – leiomyosarcoma – sternum – minimally invasive metastasectomy – adrenalectomy
Authors: Ioannidis Orestis, Kotidis Efstathios, Anestiadou Elissavet, Matzarakis Ioannis, Skliris James Philip, Symeonidis Savvas, Bitsianis Stefanos, Kerasidou Ourania, Kaprianou Magda, Chatzianestiadou Christiana, Salta-Poupnara Eleni, Tserkezidis Freiderikos, Angelopolos Konstantinos, Angelopoulos Stamatios2025-08-15:Laparoscopic resection of retroperitoneal metastasis originating from sternal leiomyosarcoma – a case report
Klin Onkol 2025; 38(4): 307-309.
DOI: 10.48095/ccko2025307.
Authors: Richter Igor, Bartoš Jiří, Dvořák Josef2025-08-15:Commentary on the CheckMate 9ER clinical trial
Authors: Richter Igor, Bartoš Jiří, Dvořák Josef2025-08-15:Commentary on the CheckMate 9ER clinical trial
Klin Onkol 2025; 38(3): 170-176.
DOI: 10.48095/ccko2025170.
Keywords: GIST – imatinib – sunitinib – regorafenib – ripretinib – avapritinib – systemic treatment
Authors: Batko Stanislav2025-06-15:Present management of gastrointestinal stromal tumors
Keywords: GIST – imatinib – sunitinib – regorafenib – ripretinib – avapritinib – systemic treatment
Authors: Batko Stanislav2025-06-15:Present management of gastrointestinal stromal tumors
Klin Onkol 2025; 38(3): 177-184.
DOI: 10.48095/ccko2025177.
Keywords: elderly age – incidence – mortality – cancer
Authors: Ondrušová Martina, Vándor Svidová Soňa, Blažová Adriána, Ondruš Dalibor2025-06-15:Cancer in the elderly in Slovakia
Keywords: elderly age – incidence – mortality – cancer
Authors: Ondrušová Martina, Vándor Svidová Soňa, Blažová Adriána, Ondruš Dalibor2025-06-15:Cancer in the elderly in Slovakia
Klin Onkol 2025; 38(3): 185-191.
DOI: 10.48095/ccko2025185.
Keywords: early cervical cancer – locally advanced cervical cancer – external beam radiotherapy – brachytherapy – pembrolizumab
Authors: Soumarová Renata2025-06-15:Current complex treatment for cervical cancer
Keywords: early cervical cancer – locally advanced cervical cancer – external beam radiotherapy – brachytherapy – pembrolizumab
Authors: Soumarová Renata2025-06-15:Current complex treatment for cervical cancer
Klin Onkol 2025; 38(3): 192-200.
DOI: 10.48095/ccko2025192.
Keywords: carcinoma – non-small-cell lung – Czech Republic – immunotherapy – pembrolizumab monotherapy – programmed death-ligand 1 – real-world data
Authors: Santorelli Melissa L., Chrápavá Marika, Hrabcová Karolína, Bencina Goran, Blažek Jiří , Bratová Monika , Fibigr Ondřej, Fischer Ondřej, Koubková Leona, Krejčí Jana, Ryška Aleš, Zemanová Petra, Burke Thomas2025-06-15:Real-world PD-L1 testing, first-line therapy for advanced NSCLC, and first-line pembrolizumab monotherapy utilization and outcomes for metastatic NSCLC in the Czech Republic
Keywords: carcinoma – non-small-cell lung – Czech Republic – immunotherapy – pembrolizumab monotherapy – programmed death-ligand 1 – real-world data
Authors: Santorelli Melissa L., Chrápavá Marika, Hrabcová Karolína, Bencina Goran, Blažek Jiří , Bratová Monika , Fibigr Ondřej, Fischer Ondřej, Koubková Leona, Krejčí Jana, Ryška Aleš, Zemanová Petra, Burke Thomas2025-06-15:Real-world PD-L1 testing, first-line therapy for advanced NSCLC, and first-line pembrolizumab monotherapy utilization and outcomes for metastatic NSCLC in the Czech Republic
Klin Onkol 2025; 38(3): 201-208.
DOI: 10.48095/ccko2025201.
Keywords: cancer of the uterine cervix – operative surgical procedure – intermediate-risk factors – adjuvant radiotherapy
Authors: Sorokin Pavel, Kulikova Svetlana, Stepanyan Artem, Davtyan Hasmik, Kuryllo Marek, Oliveira Rivadavio, Rezende Bruno2025-06-15:Total mesometrial resection for the treatment of cervical cancer – an exploratory study of feasibility, safety and oncological outcomes in developing countries
Keywords: cancer of the uterine cervix – operative surgical procedure – intermediate-risk factors – adjuvant radiotherapy
Authors: Sorokin Pavel, Kulikova Svetlana, Stepanyan Artem, Davtyan Hasmik, Kuryllo Marek, Oliveira Rivadavio, Rezende Bruno2025-06-15:Total mesometrial resection for the treatment of cervical cancer – an exploratory study of feasibility, safety and oncological outcomes in developing countries