MD Marry M. van den Heuvel-Eibrink, PhD

Publikovaná abstrakta

• A Complex Karyotype but Not Monosomy 7 Is an Independent Prognostic Factor in Advanced Childhood MDS.
• Aberrant DNA Methylation Characterizes a Subtype of Juvenile Myelomonocytic Leukemia (JMML) with Poor Outcome
• APPLICABILITY OF A REPRODUCIBLE FLOW CYTOMETRY SCORING SYSTEM IN THE DIAGNOSIS OF REFRACTORY CYTOPENIA OF CHILDHOOD
• BCOR and BCORL1 Mutations In Pediatric Acute Myeloid Leukemia
• Bone Marrow Immunophenotyping By Flow Cytometry in Refractory Cytopenia of Childhood
• BRAF Mutations in Juvenile Myelomonocytic Leukemia.
• Clonal Mutational Landscape of Childhood Myelodysplastic Syndromes
• COMPARABLE OUTCOME OF IMMUNOSUPPRESSIVE THERAPY WITH RABBIT ANTI-THYMOCYTE GLOBULIN (ATG) PLUS CYCLOSPORINE A (CSA) TO ONE WITH HORSE ATG PLUS CSA IN REFRACTORY CYTOPENIA IN CHILDHOOD
• Differences in Cyto- and Molecular Genetic Abnormalities between Children
• DNA Methylation Profiling of Pediatric AML Reveals That Hypomethylation of MN1 Is Characteristic of Inv(16) AML and a Driver of MN1 Overexpression
• ETV6 Aberrations Are a Recurrent Event in Pediatric Acute Myeloid Leukemia with Poor Clinical Outcome
• Germline Mutations in CBL Cause a Predisposition to Juvenile Myelomonocytic Leukemia
• HIGH GATA2 EXPRESSION IS A POOR PROGNOSTIC MARKER IN PEDIATRIC ACUTE MYELOID LEUKEMIA
• HLA-Identical Umbilical Cord Blood Transplantation from a Sibling Donor in Juvenile myelomonocytic Leukemia
• Characterization of CEBPA Mutations and Promoter Hypermethylation in Pediatric Acute Myeloid Leukemia
• Identification of Gene Expression Signatures Accurately Predicting Cytogenetic Subtypes in Pediatric Acute Myeloid Leukemia
• IER3 Expression in Childhood Myelodysplastic Syndrome
• IKZF1 deletions in Pediatric Acute Myeloid Leukemia
• Is Prevention of Myeloid Leukemia Possible?
• JMML Revisited: Role Und Outcome of Hematopoietic Stem Cell Transplantation in Subtypes of Juvenile Myelomonocytic Leukemia (JMML)
• LIN28B DEFINES AN AGGRESSIVE SUBTYPE OF JUVENILE MYELOMONOCYTIC LEUKAEMIA
• Microrna Expression Profiling In Pediatric Acute Myeloid Leukemia Reveals a Tumor-Suppressive Role Of Mir-9 Associated With Translocation (8;21)
• Microrna-106b~25 Cluster Is Involved in Relapsed MLL-Rearranged Pediatric AML
• MicroRNA-196a and –196b Are Differentially Expressed Between and within Cytogenetic and Molecular Subtypes of Pediatric Acute Myeloid Leukemia, and High Expression Is Correlated to Overexpression of HOX Genes
• Molecular Aberrations in 107 Children with Myelodysplastic Syndrome (MDS)
• Mutations of the Spliceosome Complex Genes Occur In Adult Patients but Are Very Rare In Children with Myeloid Neoplasia
• Myeloid Leukemia of Down Syndrome: The Results of An International Retrospective Study
• NUP98/JARID1A Is a New Recurrent Genetic Abnormality in Pediatric Acute Megakaryoblastic Leukemia with a Distinct HOX-Gene Expression Pattern
• Overexpression of BRE in Pediatric MLL-Rearranged Acute Myeloid Leukemia Associated with t(9;11)(p22;q23)
• Pediatric Acute Myeloid Leukemia with t(8;16)(p11;p13): A Distinct Clinical and Biological Entity. Results of a Collaborative Study by the International Berlin-Frankfurt-Münster AML Study Group
• Prognostic Relevance of Recurrent Genetic Aberrations in Pediatric Acute Megakaryoblastic Leukemia
• Refractory Cytopenia In Childhood (RCC) with Normal Karyotype Is Unlikely to Progress to Advanced MDS Under a Watch and Wait Strategy
• Somatic Genetic and Epigenetic Architecture of Myelodysplastic Syndromes Arising from GATA2 Deficiency
• T-Cell Receptor V CDR3 Oligoclonality Frequently Occurs in Childhood Refractory Cytopenia and Severe Aplastic Anemia.
• Telomere Length and Telomerase Complex Mutations in Pediatric Acute Myeloid Leukemia
• THE CLINICAL RELEVANCE OF BAALC AND ERG EXPRESSION LEVELS IN PEDIATRIC AML
• THE CLINICAL RELEVANCE OF MINOR PAROXYSMAL NOCTURNAL HEMOGLOBINURIA CLONES IN REFRACTORY CYTOPENIA OF CHILDHOOD – A PROSPECTIVE STUDY BY EWOG-MDS
• The Integrated Immunological Signature of Refractory Cytopenia of Childhood (RCC)
• The Mir-193 Family Antagonizes Stem Cell Pathways and Is a Potent Tumor Suppressor in Childhood and Adult Acute Myeloid Leukemia
• THE ROLE OF CBL IN RELATION TO RAS-PATHWAY ACTIVATION IN PEDIATRIC AML
• Therapy-Related Myelodysplastic Syndrome Following Treatment for Childhood Acute Lymphoblastic Leukemia: Outcome of Patients Registered in the EWOG-MDS 98/06 Studies
• Unexpected High Frequency of GATA2 Mutations in Children with Non-Familial MDS and Monosomy 7
• Wilms’ Tumor 1 Gene Mutations in Childhood Acute Myeloid Leukemia: A New Prognostic factor with Implications for MRD Detection