Aktuality z odborného tisku


Klin Onkol 2015; 28(4): 302-304.

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TBCRC009: A Multicenter Phase II Clinical Trial of Platinum Monotherapy with Biomarker Assessment in Metastatic Triple- negative Breast Cancer

Isakoff SJ, Mayer EL, He L et al.

J Clin Oncol 2015; 33(17): 1902– 1909. doi: 10.1200/ JCO.2014.57.6660. PMID: 25847936.


Effect of Low- intensity Physical Activity and Moderate- to High-intensity Physical Exercise During Adjuvant Chemotherapy on Physical Fitness, Fatigue, and Chemotherapy Completion Rates: Results of the PACES Randomized Clinical Trial

van Waart H, Stuiver MM, van Harten WH et al.

J Clin Oncol 2015; 33(17): 1918– 1927. doi: 10.1200/ JCO.2014.59.1081. PMID: 25918291.


Efficacy of Prophylactic Low- molecular Weight Heparin for Ambulatory Patients with Advanced Pancreatic Cancer: Outcomes from the CONKO- 004 Trial

Pelzer U, Opitz B, Deutschinoff G et al.

J Clin Oncol 2015; 33(18): 2028– 2234. doi: 10.1200/ JCO.2014.55.1481. PMID: 25987694.


Paclitaxel Plus Carboplatin versus Paclitaxel Plus Cisplatin in Metastatic or Recurrent Cervical Cancer: the Open- label Randomized Phase III Trial JCOG0505

Kitagawa R, Katsumata N, Shibata T et al.

J Clin Oncol 2015; 33(19): 2129– 2235. doi: 10.1200/ JCO.2014.58.4391. PMID: 25732161.


Randomized Phase III Trial of Paclitaxel Once per Week Compared with Nanoparticle Albumin-bound Nab- paclitaxel Once per Week or Ixabepilone with Bevacizumab as First-line Chemotherapy for Locally Recurrent or Metastatic Breast Cancer: CALGB 40502/ NCCTG N063H (Alliance)

Rugo HS, Barry WT, Moreno-Aspitia A et al.

J Clin Oncol 2015; 33(21): 2361– 2369. doi: 10.1200/ JCO.2014.59.5298. PMID: 26056183.


Palbociclib in Hormone-receptor- positive Advanced Breast Cancer

Turner NC, Ro J, André F et al.

N Engl J Med 2015; 373(3): 209– 219. doi: 10.1056/ NEJMoa1505270. PMID: 26030518.


Nivolumab versus Docetaxel in Advanced Squamous- cell Non- small-cell Lung Cancer

Brahmer J, Reckamp KL, Baas P et al.

N Engl J Med 2015; 373(2): 123– 135. doi: 10.1056/ NEJMoa1504627. PMID: 26028407.


Pembrolizumab versus Ipilimumab in Advanced Melanoma

Robert C, Schachter J, Long GV et al.

N Engl J Med 2015; 372(26): 2521– 2532. doi: 10.1056/ NEJMoa1503093. PMID: 25891173.


High-dose Chemoradiotherapy and Watchful Waiting for Distal Rectal Cancer: a Prospective Observational Study

Appelt AL, Ploen J, Harling H et al.

Lancet Oncol 2015. pii: S1470– 2045(15)00120– 5. doi: 10.1016/ S1470- 2045(15)00120- 5. PMID: 26156652.

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